Laboratory of Ultrastructure is an officical name changed from the old name of the electron microscopy laboratory (EMLab) on 12 August 2013. At present, the laboratory belongs to the Department of Virology, National Institute of Hygiene and Epidemiology (NIHE).
Historically, EMlab was founded in 1974 under the patronage of the Joint Committee of Science and Technology between France and Vietnam. The laboratory was firstly equipped with a transmission electron microscope (TEM) JEM-T8 with a maximum theoretical resolution of about 9Ao and other equipments for specimen preparation such as: LKB-ultramicrotome, vacuum evaporator (JEE-4B). In collaboration with other labs, the EMLab has been conducting rapid diagnoses of intectious pathogens in human, animals and plants.
In 1997, the laboratory was equipped with another transmission electron microscope (TEM, JEM1010, JEOL) with an accelerating voltage of 30- 100kV, and resolution up to 3Ao.
Historically, EMlab was founded in 1974 under the patronage of the Joint Committee of Science and Technology between France and Vietnam. The laboratory was firstly equipped with a transmission electron microscope (TEM) JEM-T8 with a maximum theoretical resolution of about 9Ao and other equipments for specimen preparation such as: LKB-ultramicrotome, vacuum evaporator (JEE-4B). In collaboration with other labs, the EMLab has been conducting rapid diagnoses of intectious pathogens in human, animals and plants.
Main building of NIHE
Prof. Hoang Thuy Nguyen introduced JEM-T8 to late Prime Minister Pham Van Dong in 1974
In 1997, the laboratory was equipped with another transmission electron microscope (TEM, JEM1010, JEOL) with an accelerating voltage of 30- 100kV, and resolution up to 3Ao.
In 2009, the laboratory was refurbished and equipped with many mordern equipments such as: high resolution scanning electron microscope (FESEM, S-4800, Hitachi), cryo-ultra microtome (UC6-FC6, Leica), ultracentrifuge (Airfuge, Beckman coulter), high vaccum evaporator (ladd research), a series of light microscopes (Nikon) and other equipments.
Thanks to all instruments equipped, the EMLab has been performed successfully many projects on the fields of medicine, biology, agriculture, nanotechnology, etc. Moreover, advaned EM techniques in the EMLab contributed significantly to recent studies on emerging and re-emerging pathogens including: SARS-CoV, influenza A/H5N1, influenza A/H1N1, arbovirus, nidovirus, Dengue virus, enterovirus, vibrio cholera etc.
Prof. Nguyen Van Man (sitting on the right, NIHE); Assoc. Prof. Nguyen Kim Giao (standing on the right, NIHE); Ms Nguyen Thi Minh Lien (standing on the left, NIHE) and Colonelcy, Prof. Nguyen Quy Tao (Vietnam Military Medical University)
Thanks to all instruments equipped, the EMLab has been performed successfully many projects on the fields of medicine, biology, agriculture, nanotechnology, etc. Moreover, advaned EM techniques in the EMLab contributed significantly to recent studies on emerging and re-emerging pathogens including: SARS-CoV, influenza A/H5N1, influenza A/H1N1, arbovirus, nidovirus, Dengue virus, enterovirus, vibrio cholera etc.
Many national and international conferences, seminars and training courses on EM, have been organized successfully by the lab., for example: the bilateral seminar between Vietnam and Japan (1997), the fourth ASEAN Conference on EM (2004), and national electron microscopy training course (2006) etc.
Anually, many under- and post-graduate students coming from national institutes and universities visit and practice in our laboratory for EM techniques and analysis of their samples.
EM is currently widely applied for structural and functional researches on macromolecular structures, immuno-cytochemistry and nanotechnology. The state of the art of EM technologies combined with other research methods will therefore provide a comprehensive and higly detailed information also on the main research subjects for the EM facilty at NIHE.
EM is currently widely applied for structural and functional researches on macromolecular structures, immuno-cytochemistry and nanotechnology. The state of the art of EM technologies combined with other research methods will therefore provide a comprehensive and higly detailed information also on the main research subjects for the EM facilty at NIHE.
Recently, Laboratory of Ultrastructure focuses on three main research areas including: biological ultrastructures and immunocytochemistry (tissues, cells, virus, bacteria and fungi etc.); nanobiomedicine (nanomaterials against pathogens, biosensors/biochips, nanotoxicity, bionanomaterials etc.); hygiene and sanitation (water filter systems for heavy metals and infectious pathogens etc.)
Brief history
- Founded in 1974 (Decision by Prof. Hoàng Thủy Nguyên - Former Director of NIHE)
- Heads of the EMlab:
Prof. Nguyễn Văn Mẫn PhD., : 1974 – 1992
Assoc. Prof. Nguyễn Kim Giao PhD., : 1992 – 2005
Ms. Nguyễn Thanh Thủy MSc., : 2007 -2012- Head of the Laboratory of Ultrastructure:
Ms. Nguyễn Thanh Thủy MSc., : 2013- present
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